Chloë Sevigny made her film debut in the highly acclaimed and controversial hit KIDS. Directed by photographer Larry Clark, with a script by Harmony Korine, the film features a group of kids actually pulled from the streets of New York, as opposed to professional actors. Sevigny stars in the role of Jennie, which was the only part originally given to a professional actor. But with only a few days before shooting began, Korine and Clark felt that the part would be better served by Sevigny in the starring role. With a surprise midnight screening at Sundance and a spot in the main competition at the Cannes Film Festival, Chloe's film career was well underway. She followed up with Steve Buscemi's TREES LOUNGE, Harmony Korine's GUMMO, for which Sevigny also was costume designer, and Whit Stillman's THE LAST DAYS OF DISCO, and again for Korine in JULIEN DONKEY BOY. Sevigny also starred in two Off-Broadway plays for director Scott Elliot: Hazelwood Jr. High, written by Rob Urbinati and What The Butler Saw, written by Joe Orton.

In 1999, Sevigny emerged as one of Hollywood's most critically acclaimed young actresses, starring in Fox Searchlight Pictures' BOYS DON'T CRY. She received nominations for an Academy Award, a Golden Globe, and a Screen Actors' Guild Award, as well as winning an Independent Spirit Award, the Los Angeles Film Critics Award, the Boston Film Critics Award, Chicago Film Critics Award and the National Society of Film Critics Award.

Other film credits followed including A MAP OF THE WORLD, starring Sigourney Weaver and Julianne Moore; AMERICAN PSYCHO; Lars von Trier's DOGVILLE, with Nicole Kidman and Paul Bettany; SHATTERED GLASS, with Hayden Christiansen and Peter Sarsgaard; PARTY MONSTER, with Macauley Culkin, and DEMONLOVER, directed by Olivier Assayas.